Practice of Epidemiology Prospective Study of Particulate Air Pollution Exposures, Subclinical Atherosclerosis, and Clinical Cardiovascular Disease The Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air)
نویسندگان
چکیده
Joel D. Kaufman*, Sara D. Adar, Ryan W. Allen, R. Graham Barr, Matthew J. Budoff, Gregory L. Burke, Adrian M. Casillas, Martin A. Cohen, Cynthia L. Curl, Martha L. Daviglus, Ana V. Diez Roux, David R. Jacobs Jr., Richard A. Kronmal, Timothy V. Larson, Sally Lee-Jane Liu, Thomas Lumley, Ana Navas-Acien, Daniel H. O’Leary, Jerome I. Rotter, Paul D. Sampson, Lianne Sheppard, David S. Siscovick, James H. Stein, Adam A. Szpiro, and Russell P. Tracy
منابع مشابه
Approach to estimating participant pollutant exposures in the Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air).
Most published epidemiology studies of long-term air pollution health effects have relied on central site monitoring to investigate regional-scale differences in exposure. Few cohort studies have had sufficient data to characterize localized variations in pollution, despite the fact that large gradients can exist over small spatial scales. Similarly, previous data have generally been limited to...
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BACKGROUND Epidemiologic studies of fine particulate matter [aerodynamic diameter ≤ 2.5 μm (PM(2.5))] typically use outdoor concentrations as exposure surrogates. Failure to account for variation in residential infiltration efficiencies (F(inf)) will affect epidemiologic study results. OBJECTIVE We aimed to develop models to predict F(inf) for > 6,000 homes in the Multi-Ethnic Study of Athero...
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BACKGROUND Long- and short-term exposures to air pollution, especially fine particulate matter (PM(2.5)), have been linked to cardiovascular morbidity and mortality. One hypothesized mechanism for these associations involves microvascular effects. Retinal photography provides a novel, in vivo approach to examine the association of air pollution with changes in the human microvasculature. METH...
متن کاملAir pollution and cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis.
Research to date demonstrates a relationship between exposure to ambient air pollutants and cardiovascular disease (CVD). Many studies have shown associations between short-term exposures to elevated levels of air pollutants and CVD events, and several cohort studies suggest effects of long-term exposure on cardiovascular mortality, coronary heart disease events, and stroke. The biologic mechan...
متن کاملAir Pollution and Atherosclerosis: New Evidence to Support Air Quality Policies
Increasing attention is being paid to the subject of air pollution, with the bulk of previous work being done in animal models suggesting that exposure to air pollution causes atherosclerosis—stiffening and calcification of the arteries—in rabbits and mice [1,2]. The new findings of Sara Adar and colleagues, published in this week’s PLOS Medicine [3], take us a step forward in clarifying the br...
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